Thrombophilia screen
  • 12 Dec 2023
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Thrombophilia screen

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Article summary

Routine thrombophilia testing is not necessary before initiating HRT.


WHEN SHOULD A THROMBOPHILIA SCREEN BE PERFORMED?

NICE says:

  • Consider testing for antiphospholipid antibodies in people who have had unprovoked DVT or PE if it is planned to stop anticoagulation treatment, but be aware that these tests can be affected by anticoagulants and specialist advice may be needed.
  • Consider testing for hereditary thrombophilia in people who have had unprovoked DVT or PE and who have a first‑degree relative who has had DVT or PE if it is planned to stop anticoagulation treatment but be aware that these tests can be affected by anticoagulants and specialist advice may be needed.
  • Do not offer thrombophilia testing in people who have had provoked DVT or PE.
  • Do not offer testing for hereditary thrombophilia in people who are continuing anticoagulant treatment.

For more information on thrombophilia testing, see:

  1. British Society for Haematology Guideline.
  2. NICE Guidance. Section 1.9

NOTE:

  • A negative thrombophilia screen does not exclude a thrombophilia.
References and Further Information:

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