Skin reactions

Transdermal preparations can cause localised skin reactions.

These are more common with patches compared to gels or sprays, and may include:
• Localised skin reactions.
• Erythema.
• Itching.
• Eczema.
• Scaling.
• Blisters.
• Burning sensations.

STRATEGIES TO REDUCE SKIN REACTIONS:

1. REPOSITION PATCH

• Application to a different area of skin can sometimes improve tolerability. Patches can be applied to skin sites on the lower half of the body and some options include the buttock cheek, lower abdomen or thigh.

2. TRY AN ALTERNATIVE PATCH

• In general, the Estradot patch is associated with the fewest skin reactions and is the smallest patch.

3. TRY AN ALTERNATIVE PREPARATION

• An alternative preparation can be tried. If using patches, the gel or spray may be better tolerated. If no risk factors for VTE or stroke, the oral route can be considered.