Side effects

Updated on 28 Nov 2023
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Side effects are more likely to happen at treatment initiation when the vaginal epithelium is at its thinnest. After 2–4 weeks of treatment, the vaginal epithelium thickens and absorption is minimal.

Side effects might include:

Breast tenderness.
Vaginal bleeding.
Nausea.
Skin irritations.
Thrush.
New odour or discharge.

References and Further Information:

NAMS position statement. The 2020 genitourinary syndrome of menopause statement of The North American Menopause Society. The Journal of the North American Menopause Society. Vol 27 (9). 2020. Page 981.

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