Red flags
  • 28 Nov 2023
  • 1 Minute to read
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Red flags

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Article summary

The below are examples of gynaecological red flags. Other red flags can exist, and clinical acumen is required. If red flags are present, consider urgent referral.

For more information on gynaecological symptoms and red flags, see NICE CKS guidance.

Endometrial cancer 
  • Post menopausal bleeding (vaginal bleeding >12 months since last menstrual period)
  • Bleeding after a spell of amenorrhoea
  • Bleeding that does not settle after using continuous combined HRT for 6 months
  • Persistent intermenstrual bleeding
  • Abnormal endometrial thickness or appearance on ultrasound scan 
Cervical cancer 
  • Post coital bleeding with no obvious cause such as infection 
  • Persistent intermenstrual bleeding
  • Abnormal appearance of the cervix
Ovarian cancer 
  • Appetite loss, early satiety, abdominal distension
  • Persistent urinary urgency or frequency in women >50 years
  • New IBS symptoms in women >50 years or unexplained change in bowel habit
  • Fatigue and weight loss
  • Ascites or pelvic mass that is not obviously fibroids
  • Elevated CA125 or abnormal appearance of ovary on scan
Vaginal cancer 
  • Unexplained palpable mass at entrance to vagina
Vulval cancer 
  • Unexplained vulval lump, ulceration or bleeding
References and Further Information:

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