Cautions

Testosterone should be avoided or used with caution in:

• Women with high cardiometabolic risk or active liver disease (due to a lack of safety data).
• Where there is a history of breast cancer –off label exceptions may be agreed in women with intractable symptoms not responding to non-hormonal alternatives. These cases should be discussed with a menopause specialist and/or the breast or oncology team.
• Competitive athletes. Care must be taken to maintain levels well within the normal female physiological range.
• Women with upper normal or high baseline total testosterone levels.
• Pregnant or breast-feeding women.