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| Advantages | Disadvantages |
| Creams or gels | - May offer a soothing effect
- Can be digitally applied to the skin both internally and externally as a targeted treatment
- Can be applied with a finger
- Helpful for dryness at the introitus
| - Might be considered messy (particularly use of estriol 0.01% which is a higher volume preparation)
- There have been reports of skin sensitivities
- User has responsibility for preparing the dose
|
| Tablets or pessaries | - Convenient and practical
- Dose is confined to a singular pessary
- May be considered less messy than creams and gels
- Vagirux has a reusable applicator which is environmentally friendly
- Imvaggis does not require an applicator
| - Vaginal discharge can occur
|
| Ring | - Requires replacement only four times per year
- Long acting
- Convenient for those with busy schedules or cognitive decline
- Can be placed above a ring pessary
- No discharge
- Can remain in place during intercourse or be removed if preferred
- User can self insert
| - Potential to dislodge during a bowel movement, straining or intercourse
- More likely to dislodge if prolapse is present
- Clinical implications of potential male partner absorption are not known
|
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