- 28 Nov 2023
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ADHD
- Updated on 28 Nov 2023
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Attention deficit hyperactivity disorder (ADHD) is defined as a persistent pattern of inattention and or hyperactivity-impulsivity that interferes with functioning or development.
Like other types of neurodiversity, currently there are no specific studies that examine the impact of menopause in women with ADHD, and it represents an area where further research is needed.
Small studies have suggested that ADHD symptoms may change across the menstrual cycle. One study undertaken by Roberts and Colleagues of 32 women reported decreased levels of oestrogen being associated with higher ADHD symptoms on the following day.
There is biological plausibility to support this finding because oestrogen can modulate the function of intracranial neurotransmitters, including dopamine, which plays a central role in ADHD and executive functioning. However, without larger studies, definitive conclusions cannot be made.
In a prospective study undertaken by Groenman and Colleagues in 2022, increased menopausal symptoms such as hot flushes, poor sleep, increased anxiety, poor concentration and memory lapses were found in women who had ADHD, compared to neurotypical women.
As hormone changes take place during the menopause, patients with ADHD may report changes in their symptoms and re-evaluation of treatment regimens may be helpful.
- Groenman A, Torenvliet C, Guerts H et al. Menstruation and menopause in autistic adults: periods of importance? Autism 2021.
- Russell J, Jones C, Newhouse P. The role of oestrogen in the brain and cognitive aging. Neurotherapeutics. 2019..
- Roberts B, Eisenlohr-Moul T, Martel M. Reproductive steroids and ADHD symptoms across the menstrual cycle. Psychoneuroendocrinology. 2018.
- NICE CKS Guidance. Attention deficit hyperactivity disorder. Background information. Definition. Last revised August 2023.
- Females with ADHD and expert consensus statement. BMC Psychiatry 2020.