Contraindications
- 01 Dec 2023
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Contraindications
- Updated on 01 Dec 2023
- 1 Minute to read
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Do not prescribe HRT in women with:
- Current, past or suspected breast cancer.
- Current, past or suspected ductal carcinoma in situ (DCIS).
- Current, past or suspected oestrogen dependent cancer.
- Undiagnosed vaginal bleeding.
- Untreated endometrial hyperplasia.
- Active or recent arterial thromboembolic disease.
- Active liver disease with abnormal liver function tests.
- Pregnancy.
Prescribe HRT with caution in women with:
- Women at increased risk of breast cancer (seek guidance from menopause specialist or breast team).
- Thrombophilia disorder or past history of VTE (seek guidance from menopause specialist or haematologist).
- Factors predisposing to VTE (seek guidance from menopause specialist or haematologist).
- Previous thrombotic stroke or MI (seek guidance from menopause specialist).
- History of endometrial hyperplasia.
- Epilespy who use Lamotrigine.
- Porphyria cutanea tarda.
- Meningioma.
- Macroprolactinoma.
- Nut or soya allergy (contained in some HRT types).
- Veganism (gelatin and animal tallow is found in some HRT types).
- Lactose intolerance (most oral tablets contain lactose).
Note:
The decision to start HRT in the setting of a known caution or contraindication can sometimes be made after a detailed risk benefit discussion with a specialist.
References and Further Information:
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